Girl Start -- this site has a wide variety of games and another things that appeal to young girls

West Point Bridge Designer -- this software was designed for a national bridge contest, but you can play it for fun.  Design and build a bridge, then drive heavy trucks over it to test your design

Space Hopper Game -- it gives you a picture of a constellation, see if you can guess which one it is

Proton Don -- see if you can guess the symbols on the periodic table when the game gives you the name.  Great practice for General Chemistry class!

Stay Afloat -- this game is just like hangman, and you get to pick what subject to play

Zeeks.com -- this site is full of fun games for learning or just for fun

Jefferson Labs -- this site also has a wide selection of math, science, element, and vocabulary games.