BPchange Dose Run Treatment Animal 01 0.50 6.25 C1 Control R1 02 4.50 12.50 C1 Control R1 03 10.00 25.00 C1 Control R1 04 26.00 50.00 C1 Control R1 05 37.00 100.00 C1 Control R1 06 32.00 200.00 C1 Control R1 07 1.00 6.25 C2 Control R2 08 1.25 12.50 C2 Control R2 09 4.00 25.00 C2 Control R2 10 12.00 50.00 C2 Control R2 11 27.00 100.00 C2 Control R2 12 29.00 200.00 C2 Control R2 13 0.75 6.25 C3 Control R3 14 3.00 12.50 C3 Control R3 15 3.00 25.00 C3 Control R3 16 14.00 50.00 C3 Control R3 17 22.00 100.00 C3 Control R3 18 24.00 200.00 C3 Control R3 19 1.25 6.25 C4 Control R4 20 1.50 12.50 C4 Control R4 21 6.00 25.00 C4 Control R4 22 19.00 50.00 C4 Control R4 23 33.00 100.00 C4 Control R4 24 33.00 200.00 C4 Control R4 25 1.50 6.25 C5 Control R5 26 1.50 12.50 C5 Control R5 27 5.00 25.00 C5 Control R5 28 16.00 50.00 C5 Control R5 29 20.00 100.00 C5 Control R5 30 18.00 200.00 C5 Control R5 31 1.25 6.25 M1 MDL R1 32 0.75 12.50 M1 MDL R1 33 4.00 25.00 M1 MDL R1 34 9.00 50.00 M1 MDL R1 35 25.00 100.00 M1 MDL R1 36 37.00 200.00 M1 MDL R1 37 1.40 6.25 M2 MDL R2 38 1.70 12.50 M2 MDL R2 39 1.00 25.00 M2 MDL R2 40 2.00 50.00 M2 MDL R2 41 15.00 100.00 M2 MDL R2 42 28.00 200.00 M2 MDL R2 43 0.75 6.25 M3 MDL R3 44 2.30 12.50 M3 MDL R3 45 3.00 25.00 M3 MDL R3 46 5.00 50.00 M3 MDL R3 47 26.00 100.00 M3 MDL R3 48 25.00 200.00 M3 MDL R3 49 2.60 6.25 M4 MDL R4 50 1.20 12.50 M4 MDL R4 51 2.00 25.00 M4 MDL R4 52 3.00 50.00 M4 MDL R4 53 11.00 100.00 M4 MDL R4 54 22.00 200.00 M4 MDL R4 55 2.40 6.25 M5 MDL R5 56 2.50 12.50 M5 MDL R5 57 1.50 25.00 M5 MDL R5 58 2.00 50.00 M5 MDL R5 59 9.00 100.00 M5 MDL R5 60 19.00 200.00 M5 MDL R5